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QUESTION: I get a lot of emails for top rated penis enlargement pills. Do they really work? If they do, are there any negative side effects (deformed penis, pain, etc)? Are results lasting or do they go away after a prolonged period of not taking the pills? And any other information related to the topic? – Natural penis enlargement products.

ANSWER: To our knowledge, there are no studies that have been reported in scientific, peer-reviewed journals that suggest that taking such pills might enlarge a man’s penis, either in length or circumference.
When drug manufacturers seek approval for their medications from the US Food and Drug 

Administration (FDA), they have to be able to prove that their product is safe for individuals to take, that it is effective (that is, it does what it is said to do), and they also must document and publish any potential side effects.

We know of no penis enlargement pills that have FDA approval or clearance. As such, there is no way to know whether these pills work (which seems unlikely, or one might guess that a major pharmaceutical company would be manufacturing them by now and turning a huge profit). There is also no way to know whether these pills are safe for individuals to take or whether they are associated with negative side effects. As you may know, some supplements (even herbal types) have been associated with serious – even potentially fatal – negative side effects.

Further, major US medical organizations do not recognize any surgical techniques as being safe and effective for what is called “penile augmentation” (a more clinical term for penis enlargement). Even though you may come across advertisements for penis enlargement surgery, such surgery has been associated with scar tissue which can cause painful erections or even a shortening of the erect penis.

Considering, then, that there do not appear to be any safe and effective methods of penile enlargement, how come they continue to be so widely marketed? Many companies prey on men’s and women’s concerns about their bodies ­(and even concerns about masculinity/feminity) – hence the huge market for diet pills, cosmetic surgery, breast enlargement pills, and yes, penis enlargement pills. And yet when it comes to penis size, most men are entirely within the normal range.

The average length of a man’s erect penis is typically about 5 to 6 inches, according to most scientific studies. However, penis size varies widely – some studies show erect length ranging from about 1 or 2 inches to 14 or 16 inches. And there is no “right” length or circumference; each has their advantages or disadvantages.

For example, even though men sometimes wish for a larger penis, they may not be aware that men of larger penis sizes sometimes report difficulty finding a sex partner for comfortable oral, vaginal or anal sex, as it may be too painful for their partner. Female partners, for example, can only take so much into their vagina (in an unaroused state, the vagina is about 3-4 inches long; in an aroused state, it expands to about 6 inches long).

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Sadly, some companies that sell penis enlargement pills provide inaccurate information on their web sites or other marketing materials suggesting that the average erect penis length is 7 inches. This false information may make men feel shorter than average. Several years ago, we even learned of a company that claimed on their web site that The Kinsey Institute had conducted research proving that their enlargement pills worked, even though we had never conducted such a study.

Further, sexual satisfaction has less to do with genital size and more to do with relationship satisfaction and partners communicating their sexual desires to one another. For an entertaining yet historical perspective on men and how various cultures (including our own) have dealt with penis size, men’s sexuality and more, check out A Mind of Its Own: A Cultural History of the Penis. To learn more about sexual techniques and communication, you might find The Good Vibrations Guide to Sex to be of interest.

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Clinical References

  • 1Klots, T., Mathers, MJ., Braun, M., Bloch, W., and Engelmann, U. (1999): ‘Effectiveness of oral L-arginine in first-line treatment of erectile dysfunction in a controlled crossover study’. Urologia Internationalis, 1999;63(4):220-3, PMID: 10743698
  • 2Chen, J., Wollman, Y., Chernichovsky, T., Iaina, A., Sofer, M., and Matzkin, H. (1999): ‘Effect of oral administration of high-dose nitric oxide donor l-arginine in men with organic erectile dysfunction: results of a double-blind, randomized, placebo-controlled study’. BJU International, 1999 Feb;83(3):269-73, PMID: 10233492
  • 3Sumner, MD., Elliott-Eller, M., Weidner, G., Daubenmier, JJ., Chew, MH., Marlin, R., Raisin, CJ., and Ornish, D. ‘Effects of Pomegranate Juice Consumption on Myocardial Perfusion in Patients with Coronary Heart Disease
  • 4Forest, CP., Padma-Nathan, H., and Liker, HR. (2007): ‘Efficacy and safety of pomegranate juice on improvement of erectile dysfunction in male patients with mild to moderate erectile dysfunction: a randomized, placebo-controlled, double-blind, crossover study.’ International Journal of Impotence Research, 2007 Nov-Dec;19(6):564-7. Epub 2007 Jun 14, PMID: 17568759
  • 5Trexler, ET., Smith-Ryan, AE., Melvin, MN., Roelofs, EJ., and Wingfield, HL. (2014): ‘Effects of pomegranate extract on blood flow and running time to exhaustion.’ Applied Physiology, Nutrition, and Metabolism, 2014 Sep;39(9):1038-42. doi:10.1139/apnm-2014-0137. Epub 2014 May 16. PMID: 25051173
  • 6Ignaro, LJ., Byrns, RE., Sumi., D, de Nigris, F., and Napoli, C. (2006): ‘Pomegranate juice protects nitric oxide against oxidative destruction and enhances the biological actions of nitric oxide.’ Nitric Oxide: Biology and Chemistry / Official Journal of the Nitric Oxide Society, 2006 Sep;15(2):93-102. Epub 2006 Apr 19. PMID: 16626982
  • 7Prasad, AS., Mantzoros, CS., Beck, FW., Hess, JW., and Brewer, GJ. (1996): ‘Zinc status and serum testosterone levels of healthy adults.’ Nutrition (Burbank, Los Angeles County, Calif.) 1996 May;12(5):344-8. PMID: 8875519
  • 8Ottaviano, G., Zuccarello, D., Frasson, G., Scarpa, B., Nardello, E., Foresta, C., Marioni, G., and Staffieri, A. (2013): ‘Olfactory sensitivity and sexual desire in young adult and elderly men: An introductory investigation.’ American Journal of Rhinology & Allergy, Volume 27, Number 3, May/Jun 2013. pp.157-161(5)
  • 9Wegmuller, R., Tay, F., Zeder, C., Brnic, M., and Hurrell, RF. (2014): ‘Zinc absorption by young adults from supplemental zinc citrate is comparable with that from zinc gluconate and higher than from zinc oxide.’ The Journal of Nutrition, 2014 Feb;144(2):132-6. doi: 10.3945/jn.113.181487. Epub 2013 Nov 20. PMID: 24259556
  • 10Zhu, JS., Halpern, GM., and Jones, K. (1998): ‘The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part 1.’ Journal of Alternative and Complementary Medicine, 1998 Fall;4(3):289-303.
  • 11Ng, CF., Lee, CP., Ho, AL., and Lee, VW. (2011): ‘Effect of niacin on erectile function in men suffering erectile dysfunction and dyslipidemina.’ The Journal of Sexual Medicine, 2011 Oct;8(10):2883-93. doi: 10.1111/j.1743-6109.2011.02414.x. Epub 2011 Aug 2. PMID: 2181010191

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